Propranolol for neurogenic fever
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There is abundant evidence that fever is detrimental in acute neurologic injury. Worse outcomes are reported in acute stroke, subarachnoid hemorrhage, and traumatic brain injury. In addition to the various etiologies of fever in the intensive care setting, neurologic illness is a risk factor for neurogenic fevers.NF, neurogenic fever; TBI, traumatic brain injury; Patients with TBI frequently experience febrile episodes that may be of infectious or non-infectious origins. Neurogenic fever is a non-infectious source of fever in the patient with TBI.Fever: neurologic causes and complications. … Fever is a symptom of … Fever associated with neurologic disorders is also referred to as neurogenic fever.Further. In up to 29% of neurologic intensive care patients. the concept of a neurogenic fever induced normothermia in 18 patients with SAH.25 increased prostaglandin E in the cerebrospinal fluid after hemo- Given the impact of fever on the injured brain.Propranolol suppresses sympathetic outflow, slowing neuronal activity (Bullard, 1987; Strum, 2002). Bradycardia is a common side effect of propranolol, although it generally does not pose a problem with the young TBI population.
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