Furosemide bolus vs continuous infusion nejm

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Several recent randomised controlled trials have examined the clinical benefit of continuous vs. bolus furosemide in acuteThere was no difference between furosemide continuous infusion and bolus administration for all-cause mortality (four studies; n = 491; I2 = 0%; OR 1.65; 95%CI 0.93-2.91; p…Intermittent administration of furosemide vs continuous infusion preceded by a loading dose for congestive heart failure. Intermittent bolus injection versus continuous infusion of furosemide in normal adult greyhound dogs.We reasoned that continuous infusion of furosemide caused less activation of neurohumoral mechanisms, since other studies have shown that bolus administration of furosemide may activate this system.Patients who were assigned to intravenous boluses of furosemide every 12 hours were more likely to require a dose increase at 48 hours than were those assigned to continuous intravenous infusion (21% vs. 11%, P=0.01).Continuous infusion vs. intermittent bolus injection of furosemide in acute decompensated heart failure: systematic review and meta-analysis of randomised controlled trials [published online September 22, 2017].Lahav M, Regev A, Ra’anani P, Theodor E. Intermittent administra- tion of furosemide vs continuous infusion preceded by a loading doseContinuous versus bolus dosing of furosemide for patients hos- pitalized for heart failure.Continuous versus intermittent infusion of furosemide in acute .To use intermittent Intravenous Bolus versus Continuous IV Infusion Diuretic Therapy, which is better, which is safest?Permanent deafness has been reported in patients with acute kidney injury receiving furosemide continuous IV infusion dose of 80 to 160 mg/h [24].Continuous infusion versus bolus injection of loop diuretics in congestive heart failure. Cochrane Database of Systematic Reviews.Diuretic efficacy of high dose furosemide in severe heart failure: bolus injection versus continuous infusion. J Am Coll Cardiol 1996;28:37682.Furosemide, a loop diuretic drug, is frequently administered to increase urinary output. The aim of the present study was to compare efficacy and complications of continuous infusion of furosemide vs bolus injection among pediatric patients after cardiac surgery.Administering intermittent boluses of furosemide to patients with acute decompensated heart failure (ADHF) often leads to unfavorable hemodynamic changes. Continuous infusion may induce similar or greater diuresis without adverse hemodynamic consequences.Furosemide administration by continuous infusion is effective as bolus therapy in its diuretic and natriuretic effects in oliguric infants following cardiac surgery. The continuous furosemide infusion produces a greater diuresis per urinary tubular furosemide concentration.Patients were randomized to either continuous furosemide infusion without a loading dose or a twice-daily bolus, then treated >48 hours. No significant difference was found in mean change in serum creatinine between the groups (–0.02 vs 0.13 mg/dL; P=.18)…Several recent randomised controlled trials have examined the clinical benefit of continuous vs. bolus furosemide in acuteContinuous infusion of intravenous furosemide was associated with increased weight reduction (five studies; n = 516; I(2) = 0%; mean difference 0.70; 95%CI 0.12-1.28…The two modalities of diuretic therapy bolus vs continuous infusion is not statistically different thus undermining the explicable efficacy of diuretic infusion in particular5. Pearl of Wisdom. 1) Continuous infusion of furosemide or bumetanide is a very effective way to treat generalized edema.The purpose of the current study was to compare the renoprotective effects of continuous furosemide infusion and intermittent furosemide bolus therapy administered with dopamine infusion in cardiac surgical patients.In the comparison of bolus with continuous infusion, there was no significant …
available with the full text of this article at NEJM.org) and was funded entirely by
the … 12 hours and a continuous infusion, one of which contained furosemide
and the …. 1 case with both boluses vs. continuous infusion and low-dose
strategy vs.n engl j med 364;9 nejm.org march 3, 2011. 797. The new … decompensated
heart failure to receive furosemide administered intravenously by means of … In
the comparison of bolus with continuous infusion, there was no significant dif- …..
across groups (bolus vs. continuous infusion and low-dose vs. high-dose strategy
).Sep 22, 2017 … Continuous infusion vs. intermittent bolus injection of furosemide in acute
decompensated heart failure: systematic review and meta-analysis of …Jun 28, 2014 … Continuous vs bolus, 2.91 (1.28, 6.63), 0.01, 2.57 (1.01, 6.58), 0.04 …..
Continuous versus intermittent infusion of furosemide in acute …Jun 30, 2015 … Continuous infusion of furosemide in the treatment of patients with … Continuous
infusion versus bolus injection of loop diuretics in congestive heart failure. … A
meta-analysis of continuous vs intermittent infusion of loop …May 21, 2012 … A meta-analysis supports continuous infusion of furosemide but does …
Continuous infusion versus intermittent bolus furosemide in ADHF: An …Dec 3, 2017 … Compared to intermittent boluses, continuous infusions of loop diuretics …
intermittent vs. continuous and low-dose (home dose) vs. high-dose therapy … 35
%) on loop diuretics at a dose equivalent to furosemide 134mg/day.Mar 4, 2011 … As for continuous vs intermittent bolus dosing, no significant … From Baseline to
72 Hours, Intermittent-Bolus vs Continuous–Infusion Groups …Oct 31, 2011 … The inclusion criteria were: random allocation to treatment, comparison of
furosemide bolus vs continuous infusion, performed in surgical or …Nov 14, 2017 … This study compared bolus doses vs. infusions and also compared low vs. high
doses of loop diuretics. … when comparing bolus or continuous infusion
administration of loop diuretic. … Click to read the study in NEJM … heart failure
on an oral daily dose of furosemide between 80-240 mg or equivalent, …However, there is controversy about the superiority of continuous infusion over ….
I. Diuretic efficiency of furosemide in continuous intravenous infusion vs. bolus …Oct 15, 2014 … In comparing low-dose and high-dose furosemide, the authors found no … When
comparing intermittent bolus with continuous infusion, the …Lasix 40 IV = 80 orally. ▫ Frequency – 2-3x/day bolus … Continuous infusion vs.
bolus. Cochrane Database … Colucci WS NEJM 2000; 343: 246. ▫ 127 patients.Mar 2, 2011 … … creatinine and clinical outcomes with higher dose of furosemide. … ADHF: 1)
route of administration (Q12 hour bolus vs. continuous infusion), …Jun 16, 2016 … Bioavailability of furosemide is highly variable (10-100%) and … of iv loop diuretic
administration (boluses vs continuous infusion) has been …age, the amount of an oral dose of furosemide that is absorbed is 50 …
Downloaded from www.nejm.org by D SHERWOOD-BERNER on April 23, 2003.
…. Single intravenous bolus doses of 160 … sider giving a continuous infusion of
a loop diuretic. ….. Pichette V, du Souich P. Role of the kidneys in the metabolism
of fu-.~15% of CHF dogs are receiving chronic furosemide at ≥6.0mg/kg/day … Bolus
vs. continuous infusion in humans: DOSE-AHF Study. Felker NEJM 2011.ProCESS, No difference in EGDT vs usual care in sepsis, NEJM. … versus low-
dose furosemide or between furosemide bolus versus infusion, NEJM 2011 (34)
….. Dulhunty, Continuous infusion of beta-lactam antibiotics achieves ↑ plasma …Jun 4, 2018 … Müller K, Gamba G, Jaquet F, Hess B. Torasemide vs. furosemide in primary …
Continuous infusion versus bolus injection of loop diuretics in …Sep 4, 2012 … Hypertonic Saline Vs. Mannitol: Dealer's Choice … Use boluses; don't use
continuous infusions of 3%, the author advises; it doesn't … Furosemide may be
provided to reduce volume expansion. … NEJM 2012;367:746-752.

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