Clozapine hypersalivation management

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    Objective: Clozapine-induced hypersalivation (CIH) is a significant side effect
    affecting about one-third of patients treated with clozapine. CIH can be
    stigmatizing …May 22, 2017 Table 1 lists treatments for clozapine-induced hypersalivation. Table 2 lists
    treatments for hypersalivation caused by other drugs. AnswerQuestion. Clozapine is naturally the ultimate choice for many of my chronic
    schizophrenic patients. However, hypersalivation is a rather common and
    irritating …Grabowski J. Clonidine treatment of clozapine-induced hypersalivation. …
    benztropine and terazosin in the treatment of hypersalivation secondary to
    clozapine.Jan 2, 2018 Aims and Method. To develop and introduce an evidence-based drug treatment
    protocol for clozapine-induced hypersalivation, a review of …Aug 20, 2012 Although several pharmacotherapeutic strategies for the treatment of CIS have …
    Current treatment strategies for clozapine-induced sialorrhea.The information contained in this document includes the use of hyoscine tablets,
    as these are usually our first line treatment option for hypersalivation, however it …In routine clinical practice, the most commonly encountered side-effects of
    clozapine are excessive salivation (drooling), somnolence, tachyarrhythmia,
    weight …One of the common side effects during the treatment with clozapine is sialorrhea.
    Although clozapine has anticholinergic side effects, pathogenesis of sialorrhea …Jun 24, 2014 This becomes relevant in considering the role of alpha-2 agonists in treatment of
    clozapine-induced sialorrhea (CIS), as they effectively reduce …Dec 19, 2013 The review excluded the antipsychotic clozapine, as its role in causing …
    Treatment of hypersalivation caused by antipsychotics or neuroleptics …To provide an understanding of the underlying pathophysiology and current
    treatment options for clozapine-induced sialorrhea. Literature was retrieved
    through …Aug 22, 2017 Moderate to low quality evidence suggests antimuscarinic may be more effective
    than placebo for reducing clozapine-induced hypersalivation.We identified articles on managing clozapine-associated AEs by searching …
    Sedation, hypersalivation, and enuresis are common but manageable with …Results 1 – 10 of 20 Evidence-based information on treat hypersalivation on clozapine from …
    Hypersalivation may occur as an adverse effect of drug treatment, …Summary Glycopyrrolate is an antimuscarinic agent that can be used
    preoperatively to inhibit drooling and excessive secretions of the respiratory tract.Jan 17, 2012 A MEDLINE search from 1975–2000 revealed that treatment of clozapine
    induced sialorrhea is predominantly based on case reports. Due to its …Aug 21, 2014 Condition or disease, Intervention/treatment, Phase. Clozapine-induced
    Hypersalivation, Drug: Metoclopramide Drug: placebo, Phase 3 …ABSTRACT. Clozapine-induced sialorrhea (CIS) is a common, treatment-limiting,
    and stigmatizing side effect. All systemic agents that are used for CIS may …Jun 25, 2018 In addition, clozapine is an effective treatment for schizophrenia ….. Excessive
    salivationClozapine-induced hypersalivation is a common …

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